We had some wierd issue today after upgrade. Some of the uses complaining after upgrading to Discoverer version 10.1.2.2 they were not able to login and getting error "No Responsibilities Are Available For The Given Connection Details At Login". But this strange for us too as some of them able to login and some not. I did test their login, responsibility end date etc etc. Then thought of checking some Bug and came to Metalink. And What its a bug, it has mentioned in Note 466188.1, and suggested to apply patch 6146747 (47MB). But we do not have time to apply this patch when production is live. So need to find workaround, guess what ???? nothing big, just added "Notification" responsibility to all users having only one responsibility against their username. So we made fool of Bug and it worked :-)
Happy Troubleshooting !!!